Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892266 | 0.92 | MDM2 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1MDM2 | |
| SCHEMBL28892272 | 0.91 | KCNQ3 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1MDM2 | |
| SCHEMBL28892391 | 0.90 | CTSL (0.34) | MDM2CTSLKDM1APSEN1PSEN2 | |
| SCHEMBL28892248 | 0.90 | GBA1 (0.37) | KCNH2 | |
| SCHEMBL28892338 | 0.89 | IDO1 (0.34) | MDM2GRM2PARP1CTSLKCNH2 | |
| SCHEMBL28892351 | 0.89 | MDM2 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1MDM2 | |
| SCHEMBL28892262 | 0.88 | OXTR (0.36) | MDM2HDAC1HDAC6CTSLKDM1A | |
| SCHEMBL28892406 | 0.88 | HDAC1 (0.33) | MDM2HDAC1HDAC6KDM1APSEN1 | |
| SCHEMBL28892369 | 0.87 | LMNA (0.33) | MDM2CTSLPSEN1PSEN2APH1B | |
| SCHEMBL28892254 | 0.86 | MDM2 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558841-B | 4- (N, N-disubstituted) furan-2 (5H) -ketone derivative, preparation method and application thereof | 贵州大学 | 2022-04-12 | — | — | CN | disclosed |