Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892309 | 0.89 | KDM1A (0.35) | MAOBBCHEKDM1A | |
| SCHEMBL28892260 | 0.88 | CYP1A2 (0.33) | GRM2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3025243 | 0.87 | L3MBTL1 (0.42) | MAOBMAOAKDM1AALDH1A1TDP1 | |
| SCHEMBL28892276 | 0.85 | CTSL (0.41) | CTSLMAOBMAOA | |
| SCHEMBL29577320 | 0.85 | CTSL (0.41) | CTSLMAOBMAOA | |
| SCHEMBL28892248 | 0.84 | GBA1 (0.37) | ALDH1A1 | |
| SCHEMBL28892338 | 0.84 | IDO1 (0.34) | CTSLGRM2KDM1AIDO1PARP1 | |
| SCHEMBL28892291 | 0.84 | TSHR (0.38) | ALDH1A1PARP1 | |
| SCHEMBL28892266 | 0.83 | MDM2 (0.34) | CTSLKDM1A | |
| SCHEMBL22667146 | 0.82 | CYP2D6 (0.34) | KDM1AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558841-B | 4- (N, N-disubstituted) furan-2 (5H) -ketone derivative, preparation method and application thereof | 贵州大学 | 2022-04-12 | — | — | CN | disclosed |