Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892254 | 0.89 | MDM2 (0.34) | L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL28892260 | 0.89 | CYP1A2 (0.33) | L3MBTL1ALDH1A1TDP1LMNA | |
| SCHEMBL28892309 | 0.89 | KDM1A (0.35) | KDM1AMAOB | |
| SCHEMBL28892318 | 0.89 | NAMPT (0.34) | L3MBTL1ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL28892355 | 0.87 | GRM4 (0.37) | ALDH1A1GAAKDM4EMAOAMAOB | |
| SCHEMBL28892263 | 0.87 | CTSL (0.36) | L3MBTL1ALDH1A1TDP1KDM1AMAOA | |
| SCHEMBL28892325 | 0.87 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL2893249 | 0.86 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL28892329 | 0.86 | AR (0.38) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL28892248 | 0.86 | GBA1 (0.37) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203410-B1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2253610-B1 | Method for manufacturing of enaminocarbonyl-compounds and their use in preparing 4-aminobut-2-enolids | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | disclosed |
| US-8487112-B2 | Method for producing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| EP-2253610-A1 | Method for manufacturing 4-aminobut-2-enolids | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100204480-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE (DE) | 2010-08-12 | — | — | US | disclosed |
| EP-2203410-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009036898-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204480-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | CYP4B1, TUBB4B, EIF4B | L3MBTL1 3807/4885ALDH1A1 468/4885TDP1 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.