Methacrylic Acid

Methacrylic Acid

SCHEMBL28895001

C=C(C)C(=O)O.NC(=O)C=CCC=CC(N)=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.40
TSHR P16473 3/20 0.34
GABRR1 P24046 2/20 0.34
GABRR2 P28476 2/20 0.34
BLM P54132 2/20 0.34
GABRR3 A8MPY1 1/20 0.34
LMNA P02545 1/20 0.34
APEX1 P27695 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PPARA Q07869 1/20 0.32
ALDH1A1 P00352 2/20 0.31
FGFR4 P22455 1/20 0.31
ALOX15 P16050 2/20 0.30
HSD17B10 Q99714 2/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28330326 0.86 TSHR (0.40) TDP1TSHRGABRR1GABRR2BLM
Acetamide SCHEMBL27877987 0.84 BLM (0.44) TDP1TSHRGABRR1GABRR2BLM
Acrylamide SCHEMBL11073932 0.83 TDP1 (0.48) TDP1TSHRALDH1A1FGFR4
Methylamine SCHEMBL7738775 0.81 TSHR (0.38) TDP1TSHRGABRR1GABRR2BLM
SCHEMBL28069237 0.81 TSHR (0.41) TDP1TSHRGABRR1GABRR2BLM
SCHEMBL30262989 0.81 TSHR (0.41) TDP1TSHRGABRR1GABRR2BLM
SCHEMBL33774 0.81 TSHR (0.41) TDP1TSHRGABRR1GABRR2BLM
SCHEMBL28425318 0.80 ALDH1A1 (0.56) TDP1TSHRALDH1A1
Acrylic Acid SCHEMBL28034676 0.79 LMNA (0.50) TDP1TSHRGABRR1GABRR2BLM
Ammonia Solution, Strong SCHEMBL27914658 0.78 TSHR (0.39) TDP1TSHRGABRR1GABRR2BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111388759-B Bone cement composite material and preparation method thereof 四川大学 2021-09-07 CN disclosed
CN-111388759-A Bone cement composite material and preparation method thereof 四川大学 2020-07-10 CN disclosed