Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 12/20 | 0.48 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30085868 | 1.00 | CTSK (0.48) | CTSKKCNH2CTSSIDH2METAP2 | |
| SCHEMBL28895224 | 1.00 | CTSK (0.48) | CTSKKCNH2CTSSIDH2METAP2 | |
| SCHEMBL25458571 | 0.85 | GPR119 (0.41) | CTSKKCNH2CTSS | |
| SCHEMBL28894758 | 0.85 | AR (0.44) | CTSKKCNH2CTSS | |
| SCHEMBL28894756 | 0.85 | AR (0.44) | CTSKKCNH2CTSS | |
| SCHEMBL30085788 | 0.85 | AR (0.44) | CTSKKCNH2CTSS | |
| SCHEMBL25460017 | 0.84 | CTSS (0.48) | CTSKKCNH2CTSSUSP30 | |
| SCHEMBL25459805 | 0.83 | IDH2 (0.43) | IDH2METAP2ITGB2ICAM1ITGAL | |
| SCHEMBL28895226 | 0.83 | IDH2 (0.43) | IDH2METAP2ITGB2ICAM1ITGAL | |
| SCHEMBL30085808 | 0.83 | IDH2 (0.43) | IDH2METAP2ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | disclosed |