Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.62 |
| ▸ | CA1 | P00915 | 17/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL29222519 | 0.90 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL29080296 | 0.90 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL28582342 | 0.90 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL9130683 | 0.90 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL4450032 | 0.90 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL26690558 | 0.90 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL31038393 | 0.90 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1006722 | 0.87 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL2841686 | 0.87 | CA2 (0.78) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL166041 | 0.87 | CA2 (0.68) | CA2CA1CA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591892-A | Benzoic acid doped nickel/cobalt bimetallic MOF (metal oxide-organic framework) based water-based battery positive electrode material and preparation method and application thereof | 浙江工业大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-114318358-B | MOF-based electrocatalyst for preparing nickel/cobalt bimetal, preparation method and application | 青岛科技大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-118048660-A | Double-effect functionalized nickel-based metal organic framework electrocatalyst and preparation method thereof | 新疆蓝山屯河降解材料有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114318358-A | Modulated nickel/cobalt bimetallic MOF-based electrocatalyst, preparation method and application | 青岛科技大学 | 2022-04-12 | — | — | CN | disclosed |