Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.65 |
| ▸ | CA1 | P00915 | 17/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL320062 | 0.97 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL26690558 | 0.93 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL28535771 | 0.93 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL4450032 | 0.93 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL11577501 | 0.93 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL26133489 | 0.93 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL28582342 | 0.93 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL11577494 | 0.93 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL28895259 | 0.90 | CA2 (0.62) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL166041 | 0.90 | CA2 (0.68) | CA2CA1CA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292100-A | Preparation method of calcium terephthalate, and application of calcium terephthalate in lithium ion battery | UNIV ELECTRONIC SCIENCE & TECH | 2015-01-21 | — | — | CN | disclosed |
| US-5380593-A | Polymeric metal terephthalate and isophthalate fibers | SYNTHETIC PRODUCTS COMPANY (US) | 1995-01-10 | — | — | US | disclosed |
| US-5296585-A | Polymeric metal terephthalate and isophthalate fibers and method of making | SYNTHETIC PRODUCTS COMPANY (US) | 1994-03-22 | — | — | US | disclosed |
| US-4767657-A | SURFACE ROUGHNESS BY PRECIPITATION OF FINE PARTICLES | DIAFOIL COMPANY, LIMITED (JP) | 1988-08-30 | — | — | US | disclosed |