Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243088 | 0.80 | LMNA (0.49) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL6586596 | 0.77 | MAPT (0.44) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL7818905 | 0.77 | MAPT (0.44) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL11804496 | 0.75 | CYP1A2 (0.42) | MAPTLMNAKMT2AMEN1KDM4E | |
| SCHEMBL18893615 | 0.74 | MAPT (0.52) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL9080129 | 0.73 | MAPT (0.52) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL7222234 | 0.73 | MAPT (0.66) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL1063565 | 0.72 | ALDH1A1 (0.56) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL398701 | 0.71 | LMNA (0.73) | MAPTLMNAKMT2AMEN1HTT | |
| SCHEMBL2189271 | 0.71 | EGFR (0.51) | MAPTLMNAKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619384-B | Benzo-heterocycle derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2020-07-28 | — | — | CN | disclosed |