Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21816656 | 0.87 | SIRT6 (0.51) | MAPTALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL28423582 | 0.82 | RAB9A (0.47) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL17670180 | 0.82 | MAPT (0.55) | MAPTHTTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28481548 | 0.81 | KMT2A (0.44) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL12312118 | 0.80 | HTT (0.61) | MAPTHTTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22471048 | 0.79 | HTT (0.54) | MAPTHTTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22471036 | 0.79 | HTT (0.54) | MAPTHTTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6816455 | 0.79 | MAPT (0.59) | MAPTHTTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28836526 | 0.79 | ALDH1A1 (0.52) | MAPTHTTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28555279 | 0.78 | POLB (0.41) | MAPTHTTALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295381-A | Intermediate for synthesizing selective inhibitor for resisting protein kinase and preparation method thereof | 株式会社柳韩洋行 | 2020-06-16 | — | — | CN | claimed |
| CN-116194111-A | Heteroaryl derivatives, process for preparing the same, and pharmaceutical compositions containing the same as active ingredient | 株式会社沃若诺伊生物 | 2023-05-30 | — | — | CN | disclosed |
| CN-111295381-A | Intermediate for synthesizing selective inhibitor for resisting protein kinase and preparation method thereof | 株式会社柳韩洋行 | 2020-06-16 | — | — | CN | disclosed |