Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20591090 | 0.92 | SCD (0.50) | PKMTSHRGAASCDCYP11B2 | |
| SCHEMBL28441306 | 0.90 | PKM (0.58) | PKMTSHRGAASCDCYP11B2 | |
| SCHEMBL4150358 | 0.89 | PKM (0.74) | PKMTSHRGAACYP11B2CYP11B1 | |
| SCHEMBL28150125 | 0.88 | PKM (0.57) | PKMTSHRGAACYP11B2CYP11B1 | |
| SCHEMBL28430515 | 0.88 | PKM (0.57) | PKMTSHRGAACYP11B2CYP11B1 | |
| SCHEMBL28441301 | 0.88 | PKM (0.53) | PKMTSHRGAASCDSMN1; SMN2 | |
| SCHEMBL28436553 | 0.87 | PKM (0.59) | PKMTSHRGAAYTHDC1KMT2A | |
| SCHEMBL7009864 | 0.86 | YTHDC1 (0.46) | PKMTSHRGAASCDCYP11B2 | |
| SCHEMBL20591091 | 0.86 | SCD (0.46) | PKMTSHRGAASCDCYP11B2 | |
| SCHEMBL28151121 | 0.86 | PKM (0.54) | PKMTSHRGAACYP11B2YTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106692138-B | Application of N-benzyl imidazole amide derivative as polymyxin antibiotic synergist | 广州英赛特生物技术有限公司 | 2020-08-04 | — | — | CN | disclosed |