Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723178 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31723170 | 0.91 | MEN1 (0.46) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20918209 | 0.91 | MEN1 (0.46) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31723147 | 0.88 | KDM4E (0.56) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20918264 | 0.88 | KDM4E (0.56) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28824884 | 0.88 | MEN1 (0.47) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14266219 | 0.87 | ALDH1A1 (0.58) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20918211 | 0.87 | MCL1 (0.46) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31723134 | 0.87 | MCL1 (0.46) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28436214 | 0.83 | S1PR2 (0.42) | MEN1ALDH1A1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315730-A | Composition for preventing or treating tumor necrosis factor-related diseases comprising novel derivative as active ingredient and method for inhibiting tumor necrosis factor activity using the same | 艾伊莱布 | 2020-06-19 | — | — | CN | claimed |
| CN-111315730-A | Composition for preventing or treating tumor necrosis factor-related diseases comprising novel derivative as active ingredient and method for inhibiting tumor necrosis factor activity using the same | 艾伊莱布 | 2020-06-19 | — | — | CN | disclosed |