SCHEMBL31723147

SCHEMBL31723147

Cc1cccc(-c2oc3c(C)cccc3c(=O)c2C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.56
NPC1 O15118 2/20 0.56
MAPT P10636 2/20 0.56
RAB9A P51151 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HTT P42858 2/20 0.56
MEN1 O00255 1/20 0.56
HPGD P15428 1/20 0.56
KMT2A Q03164 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MCL1 Q07820 1/20 0.46
IP6K1 Q92551 1/20 0.43
IP6K3 Q96PC2 1/20 0.43
IP6K2 Q9UHH9 1/20 0.43
LDHA P00338 1/20 0.40
LDHB P07195 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
TTR P02766 1/20 0.40
RXRA P19793 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20918264 1.00 KDM4E (0.56) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL14266219 0.89 ALDH1A1 (0.58) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL28895627 0.88 MEN1 (0.48) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL31723178 0.88 MEN1 (0.48) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL31723146 0.85 ALDH1A1 (0.52) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL20918077 0.85 ALDH1A1 (0.52) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL20918211 0.84 MCL1 (0.46) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL31723134 0.84 MCL1 (0.46) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL20918209 0.84 MEN1 (0.46) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL31723170 0.84 MEN1 (0.46) KDM4ENPC1MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3699174-B1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2025-11-12 EP claimed