SCHEMBL31723134

SCHEMBL31723134

Cc1cccc2c(=O)c(C(=O)O)c(-c3ccc(F)c(F)c3)oc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
ABCG2 Q9UNQ0 2/20 0.40
ANO1 Q5XXA6 5/20 0.39
RARA P10276 4/20 0.39
RARB P10826 4/20 0.39
RARG P13631 4/20 0.39
BCL9 O00512 1/20 0.38
CTNNB1 P35222 1/20 0.38
TTR P02766 1/20 0.38
CYP1A1 P04798 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20918211 1.00 MCL1 (0.46) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL28895627 0.87 MEN1 (0.48) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL31723178 0.87 MEN1 (0.48) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL28824884 0.86 MEN1 (0.47) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL31723170 0.85 MEN1 (0.46) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL20918209 0.85 MEN1 (0.46) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL20918264 0.84 KDM4E (0.56) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL28429215 0.84 MEN1 (0.49) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL31723147 0.84 KDM4E (0.56) MCL1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL14266219 0.83 ALDH1A1 (0.58) MCL1MEN1KMT2ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3699174-B1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2025-11-12 EP claimed