SCHEMBL28895692

SCHEMBL28895692

O=C(O)CC(NC(=O)CO)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.60
CA4 P22748 1/20 0.60
MME P08473 6/20 0.43
RECQL P46063 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CASP3 P42574 1/20 0.42
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
CA1 P00915 1/20 0.40
EPHX2 P34913 2/20 0.39
FOLH1 Q04609 1/20 0.39
RIMKLA Q8IXN7 1/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29238597 1.00 CA2 (0.60) CA2CA4MMERECQLSMN1; SMN2
SCHEMBL29203958 1.00 CA2 (0.60) CA2CA4MMERECQLSMN1; SMN2
SCHEMBL4572564 0.84 CA2 (0.62) CA2CA4MMERECQLSMN1; SMN2
SCHEMBL13674348 0.84 CA2 (0.62) CA2CA4MMERECQLSMN1; SMN2
SCHEMBL3510050 0.83 ECE1 (0.50) CA2CA4MMECA1
SCHEMBL3510048 0.83 ECE1 (0.50) CA2CA4MMECA1
SCHEMBL4177568 0.82 CA2 (0.60) CA2CA4MMERECQLSMN1; SMN2
SCHEMBL15605900 0.82 CA2 (0.60) CA2CA4MMERECQLSMN1; SMN2
SCHEMBL4177566 0.82 CA2 (0.60) CA2CA4MMERECQLSMN1; SMN2
SCHEMBL4812263 0.81 TGFBR1 (0.56) CA2CA4MMERECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121586705-A Small molecule prostaglandin F receptor antagonists 辉凌公司 2026-02-27 CN disclosed
CN-116322673-B Radiolabeled compounds 伦敦国王学院 2025-06-10 CN disclosed
CN-115989224-B Plasma kallikrein inhibitors 默沙东有限责任公司 2025-02-25 CN disclosed
CN-119013301-A Binding agents that bind EPCAM and/or CD137 根马布股份公司 2024-11-22 CN disclosed
CN-118894908-A Multi-targeting compounds and uses thereof 成都社泰医疗科技有限公司 2024-11-05 CN disclosed
CN-118434455-A Near infrared fluorescence contrast biological imaging agent for sentinel lymph node imaging 库拉代尔外科创新公司 2024-08-02 CN disclosed
CN-113272293-B 2-Amino-N-heteroaryl-nicotinamide as NAV1.8 inhibitor 默沙东有限责任公司 2024-06-14 CN disclosed
CN-118146196-A FAP inhibitors 海德堡大学 2024-06-07 CN disclosed
CN-118084700-A Amino acid derivative and application thereof 贵州医科大学 2024-05-28 CN disclosed
CN-112367982-B Amide compounds, compositions and methods of treatment as kinase inhibitors 转化药物开发有限责任公司 2024-05-07 CN disclosed
CN-116535365-A Macrocyclic diamine derivatives and their combination with adenosine receptor antagonists as ENT inhibitors for the treatment of cancer ITEOS比利时公司 2023-08-04 CN disclosed
CN-116322673-A Radiolabeled compounds 伦敦国王学院 2023-06-23 CN disclosed
CN-116143690-A PET imaging for soluble epoxide hydrolase (sEH) 18 F-FNDP 约翰霍普金斯大学 2023-05-23 CN disclosed
CN-115989224-A Plasma kallikrein inhibitors 默沙东有限责任公司 2023-04-18 CN disclosed
CN-115884767-A Administration of SUMO activating enzyme inhibitors and anti-CD 38 antibodies 武田药品工业株式会社 2023-03-31 CN disclosed
CN-115768773-A Macrocyclic diamine derivatives as ENT inhibitors for the treatment of cancer and combinations thereof with adenosine receptor antagonists ITEOS比利时公司 2023-03-07 CN disclosed
CN-107567442-B Inhibitors of hepatitis C virus polymerase 共晶制药公司 2021-05-25 CN disclosed
CN-111658630-B Application of rosmarinic acid C in preparation of medicine for preventing and/or treating epilepsy 温州医科大学附属第一医院 2021-03-23 CN disclosed
CN-111658630-A Application of rosmarinic acid C in preparation of medicine for preventing and/or treating epilepsy 温州医科大学附属第一医院 2020-09-15 CN disclosed
CN-111328280-A Methods of making and using endoxifen 阿托萨治疗学公司 2020-06-23 CN disclosed