Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.58 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.58 |
| ▸ | ACP3 | P15309 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889581 | 1.00 | TDP1 (0.60) | TDP1LMNAKMT2ANPSR1MEN1 | |
| SCHEMBL628797 | 0.94 | LMNA (0.56) | TDP1LMNAKMT2ANPSR1MEN1 | |
| SCHEMBL28489153 | 0.89 | FFAR1 (0.61) | TDP1LMNAKMT2ANPSR1MEN1 | |
| SCHEMBL109205 | 0.87 | LMNA (0.53) | TDP1LMNAKMT2AMEN1CYP2D6 | |
| SCHEMBL1429119 | 0.86 | KMT2A (0.60) | TDP1LMNAKMT2ANPSR1MEN1 | |
| SCHEMBL15199300 | 0.85 | LMNA (0.56) | TDP1LMNAKMT2ANPSR1MEN1 | |
| SCHEMBL30438111 | 0.85 | LMNA (0.52) | TDP1LMNAKMT2AMEN1CYP2D6 | |
| SCHEMBL29067280 | 0.85 | LMNA (0.52) | TDP1LMNAKMT2AMEN1CYP2D6 | |
| SCHEMBL6484578 | 0.83 | FFAR1 (0.66) | TDP1LMNAKMT2ANPSR1MEN1 | |
| SCHEMBL2397228 | 0.83 | L3MBTL1 (0.69) | TDP1LMNAKMT2ANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | MSD K.K. (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2042478-A1 | METHOD FOR PRODUCING -DIARYL ELECTRON-WITHDRAWING GROUP SUBSTITUTED COMPOUND | Japan Science and Technology Agency (JP) | 2009-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | BMP6, GPR6, ACSL6 | TDP1 3153/4885LMNA 3282/4885KMT2A 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.