Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518151 | 0.91 | MAPT (0.54) | MAPTALDH1A1PDK1XDHCYP1A2 | |
| SCHEMBL15283631 | 0.81 | PDK1 (0.38) | MAPTPDK1XDHCYP1A2CYP2D6 | |
| SCHEMBL6221710 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9331091 | 0.79 | ALDH1A1 (0.49) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL28437849 | 0.77 | CYP1A2 (0.37) | MAPTPDK1XDHCYP1A2CYP2D6 | |
| SCHEMBL2205120 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL29581365 | 0.75 | ALDH1A1 (0.57) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL2205220 | 0.75 | ALDH1A1 (0.57) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL28374884 | 0.75 | PDK1 (0.46) | MAPTPDK1XDHSLC6A4HTR2B | |
| SCHEMBL2206732 | 0.73 | MAPT (0.48) | MAPTALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652303-B | Novel thienopyrimidine derivatives, preparation method and therapeutic use thereof | 赛诺菲 | 2020-08-04 | — | — | CN | disclosed |