SCHEMBL11518151

SCHEMBL11518151

CC(C)Oc1cc2c(cc1[N+](=O)[O-])CCN2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
ALDH1A1 P00352 1/20 0.54
PDK1 Q15118 1/20 0.41
XDH P47989 1/20 0.38
GFER P55789 1/20 0.37
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ADRA2A P08913 2/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
HTR2B P41595 2/20 0.33
CYP19A1 P11511 2/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A4 P31645 1/20 0.33
DRD3 P35462 1/20 0.33
OPRK1 P41145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28895772 0.91 MAPT (0.44) MAPTALDH1A1PDK1XDHGFER
SCHEMBL29581365 0.84 ALDH1A1 (0.57) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL2205220 0.84 ALDH1A1 (0.57) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL31510285 0.80 PARP10 (0.40) MAPTALDH1A1PDK1XDHMEN1
SCHEMBL15283631 0.79 PDK1 (0.38) MAPTPDK1XDHMEN1KMT2A
Acetic Acid SCHEMBL10988192 0.78 ALDH1A1 (0.51) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL2207168 0.78 ALDH1A1 (0.61) MAPTALDH1A1MEN1KMT2AHTR2B
SCHEMBL28374884 0.78 PDK1 (0.46) MAPTPDK1XDHMEN1KMT2A
Hydrochloric Acid SCHEMBL2206671 0.77 ALDH1A1 (0.60) MAPTALDH1A1MEN1KMT2AHTR2B
Hydrochloric Acid SCHEMBL2206887 0.77 ALDH1A1 (0.60) MAPTALDH1A1MEN1KMT2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159271-A CYCLIZATION OF A 2-HALOGENOPHENETHYLAMINE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1979-06-26 US disclosed