Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597561 | 0.91 | MAPK1 (0.43) | SIGMAR1HTTKMT2A | |
| SCHEMBL4465100 | 0.80 | KDM4E (0.49) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL15317756 | 0.80 | SIGMAR1 (0.48) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL2151575 | 0.78 | SIGMAR1 (0.43) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL11683468 | 0.78 | CACNA1G (0.45) | SIGMAR1HTTKMT2A | |
| SCHEMBL12798134 | 0.76 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL2151933 | 0.75 | DRD2 (0.44) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL2360647 | 0.75 | DRD2 (0.40) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL325460 | 0.72 | SIGMAR1 (0.50) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL595482 | 0.71 | MEN1 (0.51) | SIGMAR1HDAC4OPRM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724070-B | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-112724070-A | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-112724070-B | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112724070-B | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112724070-A | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-112724070-A | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |