Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | TPO | P07202 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30028868 | 0.84 | MPO (0.31) | MPOTPO | |
| SCHEMBL28896358 | 0.65 | MPO (0.61) | MPOTPO | |
| SCHEMBL28896535 | 0.64 | MPO (0.40) | MPOTPO | |
| SCHEMBL28896548 | 0.63 | KMT2A (0.39) | MPOTPO | |
| SCHEMBL29211286 | 0.63 | MPO (0.47) | MPOTPO | |
| SCHEMBL29211241 | 0.62 | MPO (0.47) | MPOTPO | |
| SCHEMBL30029184 | 0.62 | MPO (0.47) | MPOTPO | |
| SCHEMBL29211290 | 0.62 | MPO (0.48) | MPOTPO | |
| SCHEMBL1536715 | 0.57 | ALDH1A1 (0.42) | MPOTPO | |
| SCHEMBL30029124 | 0.53 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |