Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22820438 | 0.86 | UCHL1 (0.46) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL28961568 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL30749329 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL27224064 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL30749247 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL30899767 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL27223962 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL31413078 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL2325712 | 0.83 | NR1H2 (0.57) | ALDH1A1LMNATSHRKMT2ANPSR1 | |
| SCHEMBL3312132 | 0.83 | NR1H2 (0.57) | ALDH1A1LMNATSHRKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |