Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30029160 | 1.00 | KMT2A (0.43) | KMT2AALDH1A1MEN1SMN1; SMN2RAB9A | |
| SCHEMBL13740745 | 0.83 | FLT1 (0.34) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL28896620 | 0.81 | MGLL (0.41) | GAA | |
| SCHEMBL16099787 | 0.80 | MGLL (0.44) | KMT2AALDH1A1MEN1RAB9AKDM4E | |
| SCHEMBL20872459 | 0.72 | MCL1 (0.44) | KMT2AALDH1A1MEN1RAB9AGAA | |
| SCHEMBL21516019 | 0.71 | MALT1 (0.35) | KMT2AALDH1A1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL13740391 | 0.71 | DRD2 (0.35) | — | |
| SCHEMBL13335882 | 0.69 | KDM4E (0.39) | KMT2AALDH1A1MEN1GAAKDM4E | |
| SCHEMBL14194427 | 0.69 | — | — | |
| SCHEMBL13740479 | 0.68 | HTR1F (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |