Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896240 | 0.79 | KDM4E (0.54) | EPHX2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL4143308 | 0.76 | KMT2A (0.56) | EPHX2KMT2AALDH1A1MEN1GLA | |
| SCHEMBL9781234 | 0.76 | ALDH1A1 (0.57) | EPHX2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL18814446 | 0.75 | ALDH1A1 (0.59) | EPHX2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL10638009 | 0.74 | ALDH1A1 (0.59) | EPHX2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL1237067 | 0.74 | GLA (0.54) | KMT2AALDH1A1GLASMN1; SMN2POLB | |
| SCHEMBL1238474 | 0.74 | GLA (0.54) | KMT2AALDH1A1GLASMN1; SMN2POLB | |
| SCHEMBL29699752 | 0.73 | ALDH1A1 (0.60) | EPHX2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL29699722 | 0.73 | ALDH1A1 (0.60) | EPHX2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL2241047 | 0.73 | LDHA (0.57) | EPHX2KMT2AALDH1A1MEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |