Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896264 | 0.89 | PTGER4 (0.34) | PTGER4KDM4ENPSR1ADORA2BALDH1A1 | |
| SCHEMBL28896299 | 0.89 | PTGER4 (0.34) | PTGER4KDM4ENPSR1ADORA2BALDH1A1 | |
| SCHEMBL28896591 | 0.88 | ALDH1A1 (0.34) | PTGER4KDM4ENPSR1ALDH1A1HPGD | |
| SCHEMBL28896317 | 0.85 | ALDH1A1 (0.33) | PTGER4KDM4ENPSR1ADORA2BALDH1A1 | |
| SCHEMBL28896320 | 0.82 | JAK1 (0.37) | NPSR1MAPTKMT2A | |
| SCHEMBL28896250 | 0.77 | PTGER4 (0.38) | PTGER4KDM4ENPSR1ALDH1A1HPGD | |
| SCHEMBL28896378 | 0.76 | ALDH1A1 (0.40) | PTGER4KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28896547 | 0.74 | CNR2 (0.38) | PTGER4KDM4EALDH1A1HPGDGAA | |
| SCHEMBL1536739 | 0.73 | TSHR (0.45) | PTGER4KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28896253 | 0.73 | NUDT1 (0.38) | PTGER4KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |