Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896547 | 0.86 | CNR2 (0.38) | ALDH1A1PTGER4JAK3KDM4EKMT2A | |
| SCHEMBL8217430 | 0.84 | KMT2A (0.40) | ALDH1A1PTGER4KDM4EKMT2ANUDT1 | |
| SCHEMBL1536739 | 0.82 | TSHR (0.45) | ALDH1A1PTGER4KDM4EKMT2ANUDT1 | |
| SCHEMBL1536764 | 0.81 | LMNA (0.44) | ALDH1A1PTGER4KDM4EKMT2ANUDT1 | |
| Hydrochloric Acid SCHEMBL25312311 | 0.81 | TSHR (0.44) | ALDH1A1PTGER4KDM4EKMT2ANUDT1 | |
| SCHEMBL21530644 | 0.80 | TSHR (0.46) | ALDH1A1PTGER4KDM4EKMT2ANUDT1 | |
| SCHEMBL28896250 | 0.79 | PTGER4 (0.38) | ALDH1A1PTGER4JAK3KDM4EKMT2A | |
| SCHEMBL28896253 | 0.79 | NUDT1 (0.38) | ALDH1A1PTGER4KDM4EKMT2ANUDT1 | |
| SCHEMBL4256633 | 0.78 | RAB9A (0.46) | ALDH1A1KMT2AHPGDGAARAB9A | |
| SCHEMBL18557963 | 0.78 | KMT2A (0.43) | ALDH1A1KDM4EKMT2ANUDT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |