SCHEMBL28896997

SCHEMBL28896997

Cn1cc(C#N)c(-c2cccc(F)c2Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 1/20 0.35
DRD2 P14416 2/20 0.34
KDM1A O60341 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
IMPDH2 P12268 1/20 0.32
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 2/20 0.31
MAOA P21397 1/20 0.31
LRRK2 Q5S007 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28441632 0.84 CNR2 (0.44) DRD2KDM1AALDH1A1KDM4EGAA
SCHEMBL28450899 0.84 CYP11B1 (0.39) BCAT1ALDH1A1KDM4EGAAIMPDH2
SCHEMBL10512649 0.82 KDM4E (0.33) KDM1AALDH1A1KDM4EGAACYP11B1
Dimethylamine SCHEMBL9635420 0.81 ALOX15 (0.42) DRD2KDM1AALDH1A1KDM4EGAA
SCHEMBL28440611 0.78 L3MBTL1 (0.43) ALDH1A1KDM4EGAACNR1CNR2
SCHEMBL24084262 0.76 BCAT1 (0.43) BCAT1CYP11B1CYP11B2LRRK2
SCHEMBL28442816 0.75 CHUK (0.37) BCAT1KDM4ECNR1CNR2CYP11B1
SCHEMBL28434947 0.73 TSHR (0.41) DRD2KDM1AALDH1A1KDM4EIMPDH2
SCHEMBL24084229 0.72 PDK2 (0.43) BCAT1DRD2ALDH1A1CNR1CNR2
SCHEMBL28438987 0.72 TSHR (0.48) DRD2IMPDH2LRRK2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393348-B Nitrogen-substituted phenylpyrrole compound and application thereof in plant sterilization 黑龙江大学 2023-03-28 CN claimed
CN-111393348-A Nitrogen-substituted phenylpyrrole compound and application thereof in plant sterilization 黑龙江大学 2020-07-10 CN claimed
CN-111393348-B Nitrogen-substituted phenylpyrrole compound and application thereof in plant sterilization 黑龙江大学 2023-03-28 CN disclosed
CN-111393348-A Nitrogen-substituted phenylpyrrole compound and application thereof in plant sterilization 黑龙江大学 2020-07-10 CN disclosed