SCHEMBL28898247

SCHEMBL28898247

CC(C)(C)[Si](C)(C)CCCC[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28959100 0.74 RIPK1 (0.37)
SCHEMBL416284 0.71 LTA4H (0.38)
SCHEMBL31013244 0.71 POLB (0.46)
SCHEMBL31013243 0.71 POLB (0.46)
SCHEMBL8992480 0.70 DNM1 (0.40)
SCHEMBL8992135 0.70 DNM1 (0.40)
SCHEMBL5973636 0.70 DNM1 (0.40)
SCHEMBL561210 0.70 DNM1 (0.40)
SCHEMBL114778 0.69 LTA4H (0.38)
Hydrochloric Acid SCHEMBL27842651 0.67 LTA4H (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057833-A Synthetic route and intermediate compound of anticancer drug cabazitaxel 上海健佑生物科技有限公司 2022-09-16 CN claimed