Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28595389 | 0.85 | MEN1 (0.73) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL30050434 | 0.85 | MEN1 (0.73) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL16210700 | 0.84 | MEN1 (0.72) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL29414257 | 0.84 | MEN1 (0.72) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL17585774 | 0.84 | CYP11B1 (0.59) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL30898296 | 0.81 | KMT2A (0.64) | KMT2AMEN1ALDH1A1NPSR1TSHR | |
| SCHEMBL28931097 | 0.81 | KMT2A (0.64) | KMT2AMEN1ALDH1A1NPSR1TSHR | |
| SCHEMBL17585775 | 0.80 | CYP1A2 (0.57) | KMT2AMEN1ALDH1A1MAPTTP53 | |
| SCHEMBL17585779 | 0.80 | KMT2A (0.53) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL16221993 | 0.80 | MEN1 (0.53) | KMT2AMEN1ALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988117-B | Preparation method of 3-methylquinoxaline-2 (1H) -ketone derivatives | 湖南科技学院 | 2020-09-29 | — | — | CN | disclosed |