SCHEMBL30898296

SCHEMBL30898296

O=c1cnc2ccccc2n1Cc1ccc2ccccc2c1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.64
MEN1 O00255 1/20 0.64
VDR P11473 1/20 0.61
HTR3A P46098 1/20 0.55
KDM4E B2RXH2 8/20 0.54
ALDH1A1 P00352 8/20 0.54
HPGD P15428 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
CFTR P13569 1/20 0.50
HSD17B10 Q99714 3/20 0.49
NPSR1 Q6W5P4 1/20 0.49
GAA P10253 1/20 0.48
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.47
HCRTR2 O43614 1/20 0.46
BRD4 O60885 1/20 0.45
HTT P42858 1/20 0.45
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28931097 1.00 KMT2A (0.64) KMT2AMEN1VDRHTR3AKDM4E
SCHEMBL17585779 0.87 KMT2A (0.53) KMT2AMEN1VDRHTR3AKDM4E
SCHEMBL29414257 0.83 MEN1 (0.72) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL16210700 0.83 MEN1 (0.72) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL29201530 0.82 KMT2A (0.71) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL29201531 0.82 MEN1 (0.71) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL30050434 0.81 MEN1 (0.73) KMT2AMEN1HTR3AKDM4EALDH1A1
SCHEMBL29201529 0.81 MEN1 (0.69) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL29201528 0.81 MEN1 (0.69) KMT2AMEN1HTR3AKDM4EALDH1A1
SCHEMBL28595389 0.81 MEN1 (0.73) KMT2AMEN1HTR3AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047727-A Method for preparing quinoxaline-2, 3-diketone compound by virtue of regioselective photocatalytic oxidation 浙江工业大学台州研究院 2024-05-17 CN disclosed