Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17054175 | 0.84 | KMT2A (0.54) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL17054176 | 0.83 | ALDH1A1 (0.67) | KMT2AATMMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17054265 | 0.83 | HPGD (0.51) | P2RX7ALDH1A1POLBFFAR1 | |
| SCHEMBL28898656 | 0.83 | TSHR (0.50) | KMT2AHDAC1HDAC6MEN1HDAC2 | |
| SCHEMBL13527480 | 0.82 | HDAC2 (0.61) | HDAC1HDAC6HDAC2HDAC8ALDH1A1 | |
| SCHEMBL17054173 | 0.81 | LOXL2 (0.59) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL197699 | 0.80 | CYP11B1 (0.58) | KMT2AATMHDAC1HDAC6MEN1 | |
| SCHEMBL6241724 | 0.80 | CYP1A2 (0.57) | KMT2AATMHDAC1HDAC6MEN1 | |
| SCHEMBL17967143 | 0.80 | HDAC1 (0.57) | KMT2AATMHDAC1HDAC6MEN1 | |
| SCHEMBL17054172 | 0.79 | CYP2C9 (0.53) | KMT2AHDAC1HDAC6MEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385877-B | Dihydrofuran-2-one compound and preparation method thereof | 嘉兴学院 | 2024-02-23 | — | — | CN | disclosed |
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | disclosed |