Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17054175 | 0.84 | KMT2A (0.54) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL17054265 | 0.83 | HPGD (0.51) | POLBALDH1A1KDM4EFFAR1HPGD | |
| SCHEMBL28898679 | 0.83 | KMT2A (0.55) | POLBMEN1KMT2AALDH1A1FFAR1 | |
| SCHEMBL17054176 | 0.83 | ALDH1A1 (0.67) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL13527480 | 0.82 | HDAC2 (0.61) | ALDH1A1KDM4EHDAC1HDAC2HDAC8 | |
| SCHEMBL17054173 | 0.81 | LOXL2 (0.59) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1128782 | 0.80 | TAAR1 (0.52) | TSHRPOLBMEN1KMT2AFFAR1 | |
| SCHEMBL516422 | 0.80 | IDO1 (0.65) | TSHRPOLBMEN1KMT2AIDO1 | |
| SCHEMBL1981652 | 0.80 | HDAC1 (0.69) | HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL17054172 | 0.79 | CYP2C9 (0.53) | TSHRMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385877-B | Dihydrofuran-2-one compound and preparation method thereof | 嘉兴学院 | 2024-02-23 | — | — | CN | disclosed |
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | disclosed |