SCHEMBL28898686

SCHEMBL28898686

SC(Cc1ccccc1)OC(S)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
ANPEP P15144 1/20 0.46
TAAR1 Q96RJ0 4/20 0.44
SLC6A2 P23975 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
CYP1A2 P05177 1/20 0.43
CPA3 P15088 1/20 0.42
FOLH1 Q04609 1/20 0.42
IDO1 P14902 1/20 0.42
SLC18A2 Q05940 1/20 0.41
CYP2D6 P10635 1/20 0.41
SRR Q9GZT4 1/20 0.41
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5610606 0.81 TAAR1 (0.46) EPHX1ANPEPTAAR1SLC6A2SIGMAR1
SCHEMBL4650877 0.76 EPHX1 (0.55) EPHX1ANPEPTAAR1SLC6A2SIGMAR1
SCHEMBL8711135 0.76 EPHX1 (0.55) EPHX1ANPEPTAAR1SLC6A2SIGMAR1
Hydrochloric Acid SCHEMBL11846863 0.74 SRR (0.49) EPHX1CYP1A2CPA3FOLH1SRR
Bromide SCHEMBL1046181 0.74 EPHX1 (0.52) EPHX1ANPEPTAAR1SLC6A2SIGMAR1
SCHEMBL7889486 0.74 EPHX1 (0.52) EPHX1ANPEPTAAR1SLC6A2SIGMAR1
SCHEMBL16666612 0.73 MEN1 (0.40) EPHX1TAAR1SLC6A2SIGMAR1MAOA
SCHEMBL5146904 0.72 EPHX1 (0.50) EPHX1ANPEPTAAR1SLC6A2SIGMAR1
SCHEMBL4138291 0.72 EPHX1 (0.50) EPHX1ANPEPTAAR1SLC6A2SIGMAR1
SCHEMBL1493103 0.72 SIGMAR1 (0.58) EPHX1ANPEPTAAR1SLC6A2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772103-A Method for preparing sulfoxide compound by catalytic oxidation of thioether 华东师范大学 2023-03-10 CN disclosed
CN-110241095-B CYP119 enzyme, and mutant and application thereof 西南医科大学 2022-11-01 CN disclosed