SCHEMBL2889907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2887565	0.80	JAK2 (0.41)	JAK2JAK3JAK1NUDT1PRKCI
	SCHEMBL2881826	0.80	JAK1 (0.50)	JAK2JAK3JAK1NUDT1PRKCI
	SCHEMBL2887522	0.78	ROCK2 (0.47)	JAK2JAK3JAK1PRKCIAXL
	SCHEMBL4416215	0.77	ROCK2 (0.65)	AXLDAPK3CSF1RPRKACACDK8
	SCHEMBL2086494	0.72	JAK2 (0.60)	JAK2JAK3JAK1NUDT1PRKCI
	SCHEMBL2882671	0.72	TGFBR1 (0.45)	JAK2JAK1NUDT1PRKCIAXL
	SCHEMBL31554522	0.71	ROCK2 (0.65)	METROCK2TRPA1
	SCHEMBL2879737	0.71	ROCK2 (0.65)	METROCK2TRPA1
	SCHEMBL2882589	0.71	ADRA2B (0.45)	JAK2JAK3NUDT1PRKCIAXL
	SCHEMBL857277	0.71	CHKA (0.54)	JAK2JAK3JAK1NUDT1PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.