Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 8/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133978 | 0.82 | HTR2C (0.36) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL13224837 | 0.82 | PTGS2 (0.36) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL8927314 | 0.82 | PTGS2 (0.36) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL28468651 | 0.82 | HTR2C (0.50) | MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL13224854 | 0.82 | PTGS2 (0.36) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL13224856 | 0.82 | PTGS2 (0.36) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL4402453 | 0.82 | PTGS2 (0.36) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL4808314 | 0.79 | MAOB (0.35) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL4808878 | 0.78 | LMNA (0.35) | OPRM1MAOBHTR2AHTR2CHTR2B | |
| SCHEMBL21107627 | 0.78 | SMN1; SMN2 (0.34) | OPRM1MAOBHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620807-A | Preparation method of levomilnacipran hydrochloride impurity | 北京万全德众医药生物技术有限公司 | 2020-09-04 | — | — | CN | disclosed |