Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889868 | 0.82 | GRM1 (0.46) | HDAC6GRM1GRM4GRM7 | |
| SCHEMBL2889319 | 0.81 | GRM4 (0.43) | GRM1GRM4GRM7 | |
| SCHEMBL2884529 | 0.76 | GRM1 (0.44) | HDAC6GRM1GRM4GRM7 | |
| SCHEMBL2889985 | 0.76 | HDAC6 (0.40) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL2889983 | 0.76 | HDAC6 (0.40) | HDAC6HDAC1HDAC8HDAC5HDAC4 | |
| SCHEMBL2889338 | 0.75 | GRM4 (0.43) | HDAC6GRM1GRM4GRM7 | |
| SCHEMBL5429466 | 0.74 | GRM1 (0.51) | GRM1GRM4GRM7 | |
| SCHEMBL2892277 | 0.74 | GRM1 (0.44) | GRM1GRM4GRM7 | |
| SCHEMBL4426589 | 0.72 | LMNA (0.50) | GRM1GRM4GRM7 | |
| SCHEMBL11621300 | 0.71 | CYP3A4 (0.57) | GRM1GRM4GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-7674807-B2 | Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides | BAYER CROPSCIENCE AG (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | DDT, SQOR, CYP2S1 | HDAC6 354/4885HDAC1 413/4885HDAC8 1382/4885 |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | CHRM1, KCNH1, DDT | HDAC6 1906/4885HDAC1 893/4885HDAC8 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.