Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098667 | 0.80 | KMT2A (0.51) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL8713493 | 0.79 | KMT2A (0.58) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL19469362 | 0.79 | KMT2A (0.58) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL9509278 | 0.76 | KMT2A (0.47) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL28899436 | 0.75 | LMNA (0.43) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1418054 | 0.72 | RAB9A (0.47) | KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10711121 | 0.71 | SMN1; SMN2 (0.49) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL1317710 | 0.71 | KMT2A (0.63) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL29508624 | 0.71 | KMT2A (0.63) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL9244505 | 0.71 | KMT2A (0.54) | KMT2AMEN1CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234057-B | Preparation method of rotigotine | 成都工业学院 | 2022-12-02 | — | — | CN | claimed |