Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2589630 | 0.86 | L3MBTL1 (0.41) | L3MBTL1NR4A2KDM4EELANEOPRK1 | |
| SCHEMBL17113166 | 0.79 | L3MBTL1 (0.44) | L3MBTL1NR4A2ALDH1A1GAAKDM4E | |
| SCHEMBL28899572 | 0.78 | CYP46A1 (0.38) | NR4A2ALDH1A1KDM4ETSHRHTT | |
| SCHEMBL2588229 | 0.75 | KDM4E (0.46) | L3MBTL1NR4A2ALDH1A1GAAKDM4E | |
| SCHEMBL23925140 | 0.74 | L3MBTL1 (0.38) | L3MBTL1NR4A2ALDH1A1KDM4EOPRK1 | |
| SCHEMBL2588944 | 0.73 | PDE4D (0.40) | L3MBTL1ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL20605030 | 0.71 | CNR2 (0.38) | L3MBTL1NR4A2ALDH1A1KDM4EOPRK1 | |
| SCHEMBL29060507 | 0.70 | KDM4E (0.38) | L3MBTL1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL23421761 | 0.69 | NOTUM (0.39) | L3MBTL1ALDH1A1GAAKDM4ETSHR | |
| SCHEMBL17449301 | 0.68 | MEN1 (0.45) | L3MBTL1ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397812-A | Indazole derivatives | 豪夫迈·罗氏有限公司 | 2022-11-25 | — | — | CN | disclosed |