SCHEMBL2588944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2588229	0.90	KDM4E (0.46)	PDE4DL3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL20605030	0.86	CNR2 (0.38)	PDE4DL3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL20604777	0.83	SMN1; SMN2 (0.47)	ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2
	SCHEMBL23925140	0.82	L3MBTL1 (0.38)	PDE4DL3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL17113166	0.82	L3MBTL1 (0.44)	L3MBTL1ALDH1A1KMT2AKDM4EMEN1
	SCHEMBL2589630	0.76	L3MBTL1 (0.41)	L3MBTL1KDM4ETSHRHTTNPSR1
	SCHEMBL31431386	0.74	KMT2A (0.39)	PDE4DL3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL28899593	0.73	L3MBTL1 (0.39)	L3MBTL1ALDH1A1KDM4ETSHRHTT
	SCHEMBL2591387	0.72	PDE1A (0.40)	PDE4DL3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL16116137	0.70	NR4A2 (0.43)	L3MBTL1KMT2AKDM4ETSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.