SCHEMBL28899602

SCHEMBL28899602

COc1cccc2c1CC(O)(C(=O)OC13CC4CC(CC(C4)C1)C3)C2=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
FAAH O00519 3/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
ACHE P22303 1/20 0.39
GPR84 Q9NQS5 1/20 0.38
EPHX2 P34913 2/20 0.37
P2RX7 Q99572 2/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
NPC1 O15118 1/20 0.35
CYP17A1 P05093 2/20 0.34
CYP19A1 P11511 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28541543 0.81 CA1 (0.47) KDM4ELMNAPOLBMAPTCA1
SCHEMBL28389757 0.79 CA1 (0.39) CNR2KDM4ECA1CA2CA7
SCHEMBL28390956 0.78 L3MBTL1 (0.38) CNR2KDM4ELMNAPOLBP2RX7
SCHEMBL28540387 0.77 CA1 (0.43) KDM4ELMNAPOLBMAPTCA1
SCHEMBL28540388 0.77 CA1 (0.43) KDM4ELMNAPOLBMAPTCA1
SCHEMBL28535270 0.77 CA1 (0.43) KDM4ELMNAPOLBMAPTCA1
SCHEMBL28534914 0.77 CA1 (0.43) KDM4ELMNAPOLBMAPTCA1
SCHEMBL28899595 0.74 ACHE (0.49) CNR2KDM4ELMNAPOLBMAPT
SCHEMBL28393251 0.72 CNR2 (0.36) CNR2CA1CA2CA7CA9
SCHEMBL28395279 0.71 SIGMAR1 (0.37) CNR2KDM4EMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372507-B Novel method for preparing chiral alpha-hydroxy-beta-dicarbonyl compound by photocatalytic asymmetric oxidation 大连理工大学 2022-04-15 CN disclosed
CN-110372506-B Novel method for realizing visible light catalytic asymmetric oxidation by utilizing microreactor 大连理工大学 2022-04-15 CN disclosed