SCHEMBL28899674

SCHEMBL28899674

O=[N+]([O-])CCCCCCCCCCCCCC(Cc1ccccc1O)[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.41
CA12 O43570 6/20 0.33
CA2 P00918 6/20 0.33
CA9 Q16790 6/20 0.33
HSPA5 P11021 1/20 0.33
AKR1B1 P15121 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
MPO P05164 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CA1 P00915 1/20 0.31
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP2D6 P10635 1/20 0.31
HIF1A Q16665 1/20 0.31
CPA1 P15085 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11239755 1.00 MGLL (0.41) MGLLCA12CA2CA9HSPA5
SCHEMBL726420 0.90 HSPA5 (0.38) MGLLCA12CA2CA9HSPA5
SCHEMBL28051902 0.81 HSPA5 (0.38) MGLLCA12CA2CA9HSPA5
SCHEMBL10980612 0.80 CPA1 (0.43) CYP1A2ALDH1A1CPA1
SCHEMBL28960080 0.77 MGLL (0.53) MGLLCA12CA2CA9HSPA5
SCHEMBL11076196 0.77 MGLL (0.53) MGLLCA12CA2CA9HSPA5
SCHEMBL27686381 0.77 MGLL (0.36) MGLLALDH1A1
SCHEMBL27686233 0.77 TSHR (0.40) MGLLAKR1B1TSHR
SCHEMBL5183966 0.76 MGLL (0.50) MGLLCA12CA2CA9HSPA5
SCHEMBL11557107 0.75 THRA (0.36) KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260448-A Bio-based diisocyanate, preparation method thereof and polyurethane elastomer Evoco有限公司 2022-11-01 CN claimed