Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.74 |
| ▸ | CA1 | P00915 | 13/20 | 0.74 |
| ▸ | CA9 | Q16790 | 13/20 | 0.74 |
| ▸ | CA12 | O43570 | 12/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667916 | 0.85 | CA2 (1.00) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL671546 | 0.84 | CA2 (1.00) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL10773023 | 0.84 | TSHR (0.61) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL23086242 | 0.81 | CA2 (0.87) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL241662 | 0.80 | CA2 (0.67) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL28499329 | 0.80 | KMT2A (1.00) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL18095818 | 0.76 | CA2 (1.00) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL11745803 | 0.75 | PRMT1 (0.72) | CA2CA1CA9CA12 | |
| SCHEMBL672160 | 0.75 | CA2 (1.00) | CA2CA1CA9CA12CA4 | |
| SCHEMBL672761 | 0.75 | CA2 (1.00) | CA2CA1CA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115414480-A | Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme | 德玛医药 | 2022-12-02 | — | — | CN | disclosed |