Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HK1 | P19367 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467860 | 0.91 | ACSS2 (0.43) | F2F10PLGACSS2TSHR | |
| SCHEMBL28467879 | 0.87 | ALDH1A1 (0.47) | F2F10PLGMAPTRAB9A | |
| SCHEMBL28470605 | 0.85 | HDAC6 (0.46) | RAB9ANPC1ACSS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28476194 | 0.84 | KMT2A (0.52) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28714877 | 0.76 | KDM4E (0.40) | MAPTRAB9ANPC1ATMPYGM | |
| SCHEMBL16595231 | 0.72 | LMNA (0.45) | RAB9ANPC1ACSS2TSHRADORA2B | |
| SCHEMBL28287005 | 0.69 | MAPT (0.44) | MAPTRAB9ANPC1ATMPYGM | |
| SCHEMBL28980153 | 0.69 | ACSS2 (0.53) | MAPTRAB9ANPC1ACSS2CYP1A2 | |
| SCHEMBL5551585 | 0.68 | KDM4E (0.42) | MAPTRAB9ANPC1ATMPYGM | |
| SCHEMBL31306436 | 0.67 | MAPT (0.43) | MAPTRAB9ATSHRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105293-B | Synthesis method of C-3-difluoromethyl substituted quinoxalinone derivative | 浙江工业大学 | 2020-10-09 | — | — | CN | disclosed |