Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929227 | 0.90 | ELANE (0.44) | ELANEESR1HIF1ACYP19A1KMT2A | |
| SCHEMBL28158719 | 0.87 | ALDH1A1 (0.51) | ELANEKMT2AALDH1A1MEN1ATM | |
| SCHEMBL15547884 | 0.85 | KDM4E (0.44) | ELANEKMT2AALDH1A1MEN1POLB | |
| SCHEMBL7158311 | 0.85 | PRSS1 (0.53) | ALDH1A1FAAHZDHHC2LMNAPRSS1 | |
| SCHEMBL27628863 | 0.84 | ELANE (0.47) | ELANEESR1HIF1ACYP19A1KMT2A | |
| SCHEMBL27581241 | 0.84 | ELANE (0.59) | ELANEESR1HIF1ACYP19A1KMT2A | |
| SCHEMBL27697637 | 0.84 | ELANE (0.47) | ELANEESR1HIF1ACYP19A1KMT2A | |
| SCHEMBL27897138 | 0.84 | ELANE (0.47) | ELANEESR1HIF1ACYP19A1KMT2A | |
| SCHEMBL28124224 | 0.83 | ELANE (0.39) | ELANEESR1HIF1ACYP19A1KMT2A | |
| SCHEMBL28354092 | 0.82 | ELANE (0.46) | ELANEESR1HIF1ACYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637574-B2 | Salts of 3-pentylphenylacetic acid and pharmaceutical uses thereof | PROMETIC BIOSCIENCES, INC. (CA) | 2014-01-28 | — | — | US | disclosed |
| EP-2427417-B1 | SALTS OF 3-PENTYLPHENYLACETIC ACID AND PHARMACEUTICAL USES THEREOF | PROMETIC BIOSCIENCES INC (CA) | 2013-10-09 | — | — | EP | disclosed |
| US-20120095102-A1 | Salts of 3-Pentylphenylacetic Acid and Pharmaceutical Uses Thereof | PROMETIC PHARMA SMT LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| EP-2427417-A1 | SALTS OF 3-PENTYLPHENYLACETIC ACID AND PHARMACEUTICAL USES THEREOF | ProMetic BioSciences Inc. (CA) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127448-A1 | SALTS OF 3-PENTYLPHENYLACETIC ACID AND PHARMACEUTICAL USES THEREOF | PROMETIC BIOSCIENCES INC. (CA) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095102-A1 | Salts of 3-Pentylphenylacetic Acid and Pharmaceutical Uses Thereof | GLS, REN, PTP4A3 | ELANE 556/4885ESR1 4581/4885HIF1A 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.