Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503949 | 0.86 | ADORA2A (0.48) | ADORA2AADORA1 | |
| SCHEMBL21722597 | 0.81 | ADORA2A (0.67) | ADORA2AADORA1 | |
| SCHEMBL28470912 | 0.73 | TDP1 (0.38) | ADORA2A | |
| SCHEMBL28804334 | 0.72 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL17768716 | 0.71 | ADORA2A (0.69) | ADORA2AADORA1 | |
| SCHEMBL22552016 | 0.71 | ADORA2A (0.57) | ADORA2AADORA1 | |
| SCHEMBL29907746 | 0.71 | ADORA2A (0.57) | ADORA2AADORA1 | |
| SCHEMBL21722330 | 0.70 | ADORA2A (0.63) | ADORA2AADORA1 | |
| SCHEMBL22253900 | 0.70 | ADORA2A (0.66) | ADORA2AADORA1 | |
| SCHEMBL28466851 | 0.70 | ADORA2A (0.48) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111747954-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-112279837-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-112055709-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-111747954-A | Pyrazine compounds and uses thereof | 迪哲（江苏）医药有限公司 | 2020-10-09 | — | — | CN | disclosed |