Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315146 | 0.87 | MAPK1 (0.44) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL8937136 | 0.80 | MAPK1 (0.44) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL31134964 | 0.80 | MAPK1 (0.44) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL2888228 | 0.78 | CYP3A4 (0.45) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL125319 | 0.77 | CYP3A4 (0.43) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL29638353 | 0.77 | CYP3A4 (0.43) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL28080748 | 0.77 | MAPK1 (0.41) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL28087260 | 0.75 | MAPK1 (0.40) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL2889976 | 0.75 | TRPA1 (0.35) | MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL27873 | 0.74 | TDP1 (0.54) | MAPK1TDP1CYP3A4TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-1524289-B1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-20070149639-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | HORIKOSHI HIROSHI | 2007-06-28 | — | — | US | disclosed |
| US-7115050-B2 | Functionalized polysiloxane or polysilsesquioxane curable by ionizing or actinic radiation; and composite particles | ACUSHNET COMPANY (US) | 2006-10-03 | — | — | US | disclosed |
| US-20060030663-A1 | Functionalized polysiloxane or polysilsesquioxane curable by ionizing or actinic radiation; and composite particles | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2006-02-09 | — | — | US | disclosed |
| US-20060030426-A1 | Scratch resistant coating compositions for golf equipment | ACUSHNET COMPANY | 2006-02-09 | — | — | US | disclosed |
| EP-1524289-A1 | POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL COMPRISING THE COMPOSITION AND METHOD FOR PRODUCING THE MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-20040254258-A1 | Polymerizable composition, optical material comprising the composition and method for producing the material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | MAPK1 783/4885TDP1 4001/4885CYP3A4 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.