Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155136 | 0.83 | IDO1 (0.54) | IDO1TDO2IDO2MAPK14RORC | |
| SCHEMBL155403 | 0.80 | IDO1 (0.34) | IDO1TDO2IDO2NTRK1ACLY | |
| SCHEMBL154140 | 0.77 | NTRK1 (0.49) | IDO1TDO2IDO2NTRK1LMNA | |
| SCHEMBL29930277 | 0.77 | NTRK1 (0.49) | IDO1TDO2IDO2NTRK1LMNA | |
| SCHEMBL3404138 | 0.74 | NTRK1 (0.46) | IDO1TDO2IDO2NTRK1MAPK14 | |
| SCHEMBL157465 | 0.73 | IDO1 (0.44) | IDO1TDO2IDO2THRBMAPK14 | |
| SCHEMBL152432 | 0.73 | IDO1 (0.55) | IDO1TDO2IDO2NTRK1LMNA | |
| SCHEMBL9101800 | 0.70 | TDO2 (1.00) | IDO1TDO2IDO2NTRK1LMNA | |
| SCHEMBL22810214 | 0.70 | NOTUM (0.44) | THRBRORC | |
| SCHEMBL142587 | 0.66 | KMT2A (0.40) | THRBNTRK1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2427431-A1 | NOVEL INDICATOR PLATFORM | Biosynth AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |