Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289010 | 0.83 | IDO1 (0.54) | IDO1TDO2IDO2MAPK14GUSB | |
| SCHEMBL155109 | 0.80 | KMT2A (0.38) | IDO1TDO2IDO2MAPK14KMT2A | |
| SCHEMBL142563 | 0.79 | NTRK1 (0.48) | IDO1TDO2IDO2MAPK14KMT2A | |
| SCHEMBL154458 | 0.75 | IDO1 (0.54) | IDO1TDO2IDO2MAPK14KMT2A | |
| SCHEMBL3404138 | 0.74 | NTRK1 (0.46) | IDO1TDO2IDO2MAPK14KMT2A | |
| SCHEMBL10029987 | 0.72 | ALDH1A1 (0.52) | MAPK14KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22599783 | 0.71 | KMT2A (0.38) | IDO1TDO2IDO2MAPK14KMT2A | |
| SCHEMBL21196616 | 0.71 | IDO1 (0.45) | IDO1TDO2IDO2MAPK14KMT2A | |
| SCHEMBL31602058 | 0.71 | IDO1 (0.45) | IDO1TDO2IDO2MAPK14KMT2A | |
| SCHEMBL9412259 | 0.70 | MAPK14 (0.43) | IDO1TDO2IDO2MAPK14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2427431-A1 | NOVEL INDICATOR PLATFORM | Biosynth AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |