Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155669 | 0.85 | NTRK1 (0.53) | NTRK1MAPTLMNAHTTPRKCA | |
| SCHEMBL3402828 | 0.85 | LMNA (0.44) | NTRK1MAPTLMNAHTTPRKCA | |
| SCHEMBL3406408 | 0.84 | NTRK1 (0.49) | NTRK1MAPTLMNAHTTPRKCA | |
| SCHEMBL155136 | 0.74 | IDO1 (0.54) | LMNAIDO1TDO2IDO2KMT2A | |
| SCHEMBL289010 | 0.74 | IDO1 (0.54) | NTRK1LMNAIDO1TDO2IDO2 | |
| SCHEMBL155671 | 0.72 | MAPT (0.45) | NTRK1MAPTLMNAHTTPRKCA | |
| SCHEMBL8327395 | 0.71 | NTRK1 (0.48) | NTRK1MAPTLMNAHTTPRKCA | |
| SCHEMBL28866215 | 0.69 | CYP1A1 (0.59) | MAPTLMNAHTTPRKCAGSK3B | |
| SCHEMBL142587 | 0.69 | KMT2A (0.40) | NTRK1MAPTLMNAHTTKMT2A | |
| SCHEMBL21784548 | 0.69 | CYP1A1 (0.53) | MAPTLMNAKMT2ACYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |