Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28901212

NCC(=CF)COc1ccc(C(=O)N2CCc3ccccc3[C@@H]2c2ccccc2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.47

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.47
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
CA7 P43166 6/20 0.47
CA9 Q16790 6/20 0.47
CA14 Q9ULX7 6/20 0.47
AOC3 Q16853 6/20 0.45
TRPM8 Q7Z2W7 2/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
MAOB P27338 4/20 0.43
MAOA P21397 4/20 0.43
AOC2 O75106 3/20 0.43
DAO P14920 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21768084 0.82 AOC3 (0.52) CA1CA2CA7CA9CA14
Trifluoroacetic Acid SCHEMBL21768080 0.82 AOC3 (0.52) CA1CA2CA7CA9CA14
Trifluoroacetic Acid SCHEMBL21768159 0.82 AOC3 (0.52) CA1CA2CA7CA9CA14
Trifluoroacetic Acid SCHEMBL30089516 0.82 AOC3 (0.52) CA1CA2CA7CA9CA14
SCHEMBL21780127 0.81 CA12 (0.45) CA12CA1CA2CA7CA9
Trifluoroacetic Acid SCHEMBL21768088 0.79 AOC2 (0.53) CA12CA1CA2CA7CA9
Trifluoroacetic Acid SCHEMBL21768058 0.79 AOC2 (0.53) CA12CA1CA2CA7CA9
Trifluoroacetic Acid SCHEMBL21768086 0.79 AOC2 (0.53) CA12CA1CA2CA7CA9
SCHEMBL21780132 0.76 AOC2 (0.56) CA1CA2CA7CA9CA14
SCHEMBL21780142 0.76 AOC2 (0.56) CA1CA2CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110352188-B Fluoroallylamine derivatives and use thereof 四川科伦博泰生物医药股份有限公司 2022-11-29 CN disclosed