Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | NQO2 | P16083 | 3/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154017 | 0.87 | NQO2 (0.75) | KDM4EMEN1MAPTKMT2ANQO2 | |
| 3,5-O-Dimethylpinosylvin SCHEMBL918726 | 0.87 | KDM4E (0.79) | KDM4EMEN1USP2ALDH1A1TP53 | |
| 3,5-O-Dimethylpinosylvin SCHEMBL9419809 | 0.87 | KDM4E (0.79) | KDM4EMEN1USP2ALDH1A1TP53 | |
| 3,5-O-Dimethylpinosylvin SCHEMBL918727 | 0.87 | KDM4E (0.79) | KDM4EMEN1USP2ALDH1A1TP53 | |
| 3,5-O-Dimethylpinosylvin SCHEMBL6253954 | 0.85 | KDM4E (0.76) | KDM4EMEN1USP2ALDH1A1TP53 | |
| 3,5-O-Dimethylpinosylvin SCHEMBL27536829 | 0.83 | KDM4E (0.73) | KDM4EMEN1USP2ALDH1A1TP53 | |
| SCHEMBL18003157 | 0.82 | NFE2L2 (0.62) | KDM4EMEN1USP2ALDH1A1TP53 | |
| Pinosylvin Methyl Ether SCHEMBL30334927 | 0.80 | KDM4E (1.00) | KDM4EMEN1USP2ALDH1A1TP53 | |
| Pinosylvin Methyl Ether SCHEMBL9419826 | 0.80 | KDM4E (1.00) | KDM4EMEN1USP2ALDH1A1TP53 | |
| Pinosylvin Methyl Ether SCHEMBL29928865 | 0.80 | KDM4E (1.00) | KDM4EMEN1USP2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073273-B | Diphenylalkane compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-17 | — | — | CN | claimed |
| WO-2022194128-A1 | DIPHENYL ALKANE COMPOUND AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国医学科学院药物研究所 | 2022-09-22 | — | — | WO | claimed |
| CN-115073273-A | Diphenyl alkane compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-20 | — | — | CN | claimed |
| CN-115073273-B | Diphenylalkane compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-17 | — | — | CN | disclosed |
| WO-2022194128-A1 | DIPHENYL ALKANE COMPOUND AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国医学科学院药物研究所 | 2022-09-22 | — | — | WO | disclosed |
| CN-115073273-A | Diphenyl alkane compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-20 | — | — | CN | disclosed |