Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18584701 | 0.87 | ABHD6 (0.43) | ABHD6S1PR5NOTUMTAAR1MEN1 | |
| SCHEMBL16268894 | 0.85 | S1PR5 (0.40) | ABHD6S1PR5NOTUMTAAR1MEN1 | |
| SCHEMBL28245902 | 0.83 | S1PR5 (0.51) | ABHD6S1PR5NOTUMTAAR1MEN1 | |
| SCHEMBL22319819 | 0.82 | S1PR5 (0.47) | ABHD6S1PR5NOTUMTAAR1MEN1 | |
| SCHEMBL29421814 | 0.80 | ESR2 (0.51) | ABHD6MAPT | |
| SCHEMBL22530017 | 0.80 | ESR2 (0.51) | ABHD6MAPT | |
| SCHEMBL1550147 | 0.80 | ABHD6 (0.60) | ABHD6NOTUMTAAR1MEN1KMT2A | |
| SCHEMBL28208680 | 0.80 | NOTUM (0.35) | ABHD6NOTUMTAAR1ACEMEN1 | |
| SCHEMBL22319890 | 0.80 | S1PR5 (0.41) | ABHD6S1PR5NOTUMTAAR1MEN1 | |
| SCHEMBL5777006 | 0.80 | SMN1; SMN2 (0.44) | ABHD6NOTUMTAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |